Lamees Hegazy
Associate Professor, Medicinal Chemistry  

The research focus of Dr. Hegazy is the rational design and optimization of therapeutic compounds using molecular modeling and computational biochemistry methods. She uses molecular dynamics simulations, enhanced sampling simulations and free energy-based lead optimization to study the conformational behavior of prominent drug targets such as nuclear receptors and G Protein-Coupled Receptors (GPCRs) and design modulators that target different conformational states. She employs structure-based and ligand-based approaches for ligand design and optimization and work in close collaboration with biologists for experimental follow-up and validation. Her computational and modeling efforts make valuable contributions to the experimental field through the generation of new testable hypotheses to support the discovery of improved therapies.

Current Lab Members

Mohammad Homaidur Rahman 

Postdoctoral Research Associate
Computational Chemistry

Yunus Bekirov

Research Technician

Sara Hameed

Undergraduate Student

Former Lab Members

Preeti Mittal - Postdoctoral Research Associate

Chole Ong - Highschool Intern

Naeyma Naheda Islam - Postdoctoral Research Associate

Samantha Harker - Undergraduate Student

Sophia Kchouk - Undergrad Student