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Burris, T. P.; de Vera, I. M. S.; Cote, I.; Flaveny, C. A.; Wanninayake, U. S.; Chatterjee, A.; Walker, J. K.; Steinauer, N.; Zhang, J.; Coons, L. A.; Korach, K. S.; Cain, D. W.; Hollenberg, A. N.; Webb, P.; Forrest, D.; Jetten, A. M.; Edwards, D. P.; Grimm, S. L.; Hartig, S.; Lange, C. A.; Richer, J. K.; Sartorius, C. A.; Tetel, M.; Billon, C.; Elgendy, B.; Hegazy, L.; Griffett, K.; Peinetti, N.; Burnstein, K. L.; Hughes, T. S.; Sitaula, S.; Stayrook, K. R.; Culver, A.; Murray, M. H.; Finck, B. N.; Cidlowski, J. A. Pharmacol Rev 2023.


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Billon, C.; Sitaula, S.; Banerjee, S.; Welch, R.; Elgendy, B.; Hegazy, L.; Oh, T. G.; Kazantzis, M.; Chatterjee, A.; Chrivia, J.; Hayes, M. E.; Xu, W.; Hamilton, A.; Huss, J. M.; Zhang, L.; Walker, J. K.; Downes, M.; Evans, R. M.; Burris, T. P. -Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chem Biol 2023, 18 (4), 756–771.


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Murray, M. H.; Valfort, A. C.; Koelblen, T.; Ronin, C.; Ciesielski, F.; Chatterjee, A.; Veerakanellore, G. B.; Elgendy, B.; Walker, J. K.; Hegazy, L.; Burris, T. P. Structural Basis of Synthetic Agonist Activation of the Nuclear Receptor REV-ERB. Nat Commun 2022, 13 (1), 7131.


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Xu, W.; Graves, A.; Weisz-Hubshman, M.; Hegazy, L.; Magyar, C.; Liu, Z.; Nasiotis, E.; Samee, M. A. H.; Burris, T.; Lalani, S.; Zhang, L. Assigning Pathogenicity for TAB2 Variants Using a Novel Scalable Functional Assay and Expanding TAB2 Disease Spectrum. Hum Mol Genet 2023, 32 (6), 959–970.


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Hegazy, L.; Gill, L. E.; Pyles, K. D.; Kaiho, C.; Kchouk, S.; Finck, B. N.; McCommis, K. S.; Elgendy, B. Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening. Biomedicines 2022, 10 (2).


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Hodges, W. T.; Jarasvaraparn, C.; Ferguson, D.; Griffett, K.; Gill, L. E.; Chen, Y.; Ilagan, M. X. G.; Hegazy, L.; Elgendy, B.; Cho, K.; Patti, G. J.; McCommis, K. S.; Finck, B. N. Mitochondrial Pyruvate Carrier Inhibitors Improve Metabolic Parameters in Diet-Induced Obese Mice. J Biol Chem 2022, 298 (2), 101554.


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Elgendy, B.; Griffett, K.; Hegazy, L.; Di Fruscia, P.; Sample, K.; Schoepke, E.; Kamenecka, T. M.; Burris, T. P. Synthesis and Structure Activity Relationship of the First Class of LXR Inverse Agonists. Bioorg Chem 2022, 119, 105540.


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Fang, Y.; Hegazy, L.; Finck, B. N.; Elgendy, B. Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor. J Med Chem 2021, 64 (24), 17545–17571.


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Thissera, B.; Hallyburton, I.; Ngwa, C. J.; Cherif-Silini, H.; Hassane, A. S. I.; Anderson, M.; Campbell, L. A.; Mutter, N.; Eshelli, M.; Abdelmohsen, U. R.; Yaseen, M.; Pradel, G.; Belbahri, L.; Elgendy, B.; Hegazy, L.; Rateb, M. E. Potent Antiplasmodial Alkaloids from the Rhizobacterium Pantoea Agglomerans as Hemozoin Modulators. Bioorg Chem 2021, 115, 105215.


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Gouda, M.; Bawazeer, M.; Hegazy, L.; Azab, M.; Elagawany, M.; Rateb, M.; Yaseen, M.; Elgendy, B. Design, Synthesis and Antitumor Activity of Novel Dispiro[Oxindole-Cyclohexanone]- Pyrrolidines. Curr Pharm Des 2022, 28 (3), 198–207.


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Griffett, K.; Bedia-Diaz, G.; Hegazy, L.; de Vera, I. M. S.; Wanninayake, U. S.; Billon, C.; Koelblen, T.; Wilhelm, M. L.; Burris, T. P. The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids. Cell Chem Biol 2020, 27 (10), 1272–1284.


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Shahien, M.; Elagawany, M.; Sitaula, S.; Goher, S. S.; Burris, S. L.; Sanders, R.; Avdagic, A.; Billon, C.; Hegazy, L.; Burris, T. P.; Elgendy, B. Pan Agonists. Bioorg Chem 2020, 102, 104079.


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Ibrahim, T. S.; Salem, I. M.; Mostafa, S. M.; El-Sabbagh, O. I.; ElKhamisi, M. K. M.; Hegazy, L.; Elgendy, B. Design, Synthesis, and Pharmacological Evaluation of Novel and Selective COX-2 Inhibitors Based on Bumetanide Scaffold. Bioorg Chem 2020, 100, 103878.


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Tantawy, A. H.; Farag, S. M.; Hegazy, L.; Jiang, H.; Wang, M. Q. The Larvicidal Activity of Natural Inspired Piperine-Based Dienehydrazides against Culex Pipiens. Bioorg Chem 2020, 94, 103464.


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Goher, S. S.; Griffett, K.; Hegazy, L.; Elagawany, M.; Arief, M. M. H.; Avdagic, A.; Banerjee, S.; Burris, T. P.; Elgendy, B. Receptor Modulators Based on a 1,2,4-Triazole Scaffold. Bioorg Med Chem Lett 2019, 29 (3), 449–453.


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Elagawany, M.; Hegazy, L.; Cao, F.; Donlin, M. J.; Rath, N.; Tavis, J.; Elgendy, B. Identification of 4-Isopropyl-Thiotropolone as a Novel Anti-Microbial: Regioselective Synthesis, NMR Characterization, and Biological Evaluation. RSC Adv 2018, 8 (52), 29967–29975.


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El-Gendy, B. E. M.; Goher, S. S.; Hegazy, L. S.; Arief, M. M. H.; Burris, T. P. Recent Advances in the Medicinal Chemistry of Liver X Receptors. J Med Chem 2018, 61 (24), 10935–10956.


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El-Halawany, N.; Abd-El-Monsif, S. A.; Al-Tohamy Ahmed, F. M.; Hegazy, L.; Abdel-Shafy, H.; Abdel-Latif, M. A.; Ghazi, Y. A.; Neuhoff, C.; Salilew-Wondim, D.; Schellander, K. Complement Component 3: Characterization and Association with Mastitis Resistance in Egyptian Water Buffalo and Cattle. J Genet 2017, 96 (1), 65–73.

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